HSDB-3453

《英文MSH詞典》HSDB-3453
[入口詞] HSDB-3453
[主題詞] Aflatoxin B1
[英文釋義] A potent hepatotoxic and hepatocarcinogenic mycotoxin produced by the Aspergillus flavus group of fungi. It is also mutagenic,teratogenic,and causes immunosuppression in animals. It is found as a contaminant in peanuts,cottonseed meal,corn,and other grains. The mycotoxin requires epoxidation to aflatoxin B1 2,3-oxide for activation. Microsomal monooxygenases biotransform the toxin to the less toxic metabolites aflatoxin M1 and Q1.