Oxidase,NADPH

《英文msh詞典》Oxidase,NADPH
[入口詞] Oxidase,NADPH
[主題詞] NADPH Oxidase
[英文釋義] A plasma membrane-associated enzyme complex that catalyzes the univalent reduction of oxygen using NADPH as an electron donor. The superoxide anion formed acts as an oxidant in the phagocyte microbicidal system,proceeding through a series of electron transfer reactions that form the respiratory burst. Various genetic defects in the system result in chronic granulomatous disease (GRANULOMATOUS DISEASE,CHRONIC). (Dorland,28th ed) EC 1.6.-.