mirna

美 　英

• n.【女名】女子名
• 網(wǎng)絡(luò)微小核苷酸；核糖核酸；微小核糖核酸

英漢解釋

n.	1. 【女名】女子名

例句

A number of miRNA genes were shown to be located in fragile regions of the human genome that are associated with cancer 8.

研究結(jié)果證實，許多microRNA基因存在于那些與癌癥有關(guān)的人類基因組脆弱區(qū)域。

If the miRNA levels were too high or too low, the gene would not switch on, and the cell would not be killed.

如果miRNA級別太高或者太低，這種基因就不會被激活，當(dāng)然細(xì)胞也不會被殺死。

However, if a miRNA biomarker fingerprint can be established, a more accurate assessment would be more likely.

然而，如果一個microRNA指紋庫得以建立，更準(zhǔn)確的評估將變得可能。

The mature miRNA is incorporated into an RNA-induced silencing complex that binds to a target messenger RNA (mRNA).

成熟microRNA與目標(biāo)mRNA結(jié)合，形成了RNA誘導(dǎo)的基因沉默復(fù)合體。

A sera-miRNA fingerprint was determined for colorectal cancer as well.

血清microRNA指紋同樣能很好地診斷結(jié)腸癌。

MicroRNAs(miRNA) are a new class of noncoding RNAs, which are encoded as short inverted repeats in the genomes of animals and plants.

微RNA是新發(fā)現(xiàn)的一類非編碼RNA分子，在動植物細(xì)胞中廣泛表達(dá)，它的基因是短的反向重復(fù)序列。

This binding activity allows microRNAs to silence the expression of select genes in a targeted manner.

這種結(jié)合活性使得miRNA得以定向沉默目標(biāo)基因。

Kaplan-Meier survival curves were constructed using mean miRNA expression (high vs low) as threshold and compared by log-rank analysis.

平均微RNA表達(dá)水平（高表達(dá)vs低表達(dá)）作為閾值形成卡普蘭-邁耶存活曲線與時序分析形成的階梯曲線加以比較。

Through various techniques, numerous groups have gone on to show that different cancer types have distinct miRNA profiles.

應(yīng)用各種不同的技術(shù)，許多研究小組一直在試圖尋找不同癌癥的特異性microRNA表達(dá)譜。

Meanwhile, these studies show that analyzing miRNA levels in serum is a promising area for identifying biomarkers of cancer.

同時，這些研究也證實，血清microRNA的測定是一個檢測癌癥生物學(xué)標(biāo)志物很有前途的領(lǐng)域。

Therefore, their stability makes miRNA levels well suited for being tested in patient samples.

因此，它們的穩(wěn)定性使得其實際值與在病人身上得到的測試值吻合的很好。

The study examined human pancreatic tumor tissue and compared it to nearby normal tissue and control tissue for levels of microRNA (miRNA).

該研究檢測比較了人類胰腺癌組織與周圍的正常組織和對照組織中小分子RNA（miRNA）水平。

The special gene would turn on in the presence of miRNA levels that match the HeLa profile.

這種特殊的基因能夠在miRNA級別與HeLa特征相匹配時被激活。

This microRNA cluster could represent a new therapeutic target for treating tumors caused by Rb deficiency.

這種miRNA簇可以為治療Rb缺失引致的腫瘤提供新的靶點(diǎn)。

More recent research has shown that miRNAs also play an important role in cancer.

最近的研究已經(jīng)表明miRNA也在癌癥中發(fā)揮重要作用。

Scientists have now identified more than 470 different miRNAs in humans.

科學(xué)家們目前已經(jīng)在人體內(nèi)發(fā)現(xiàn)了470多種不同的miRNA。

The first serum-miRNA biomarker discovered was miR-21. Lawrie et al.

第一個被發(fā)現(xiàn)的血清microRNA標(biāo)志物是miR-21。

Each evening when I arrived home, Mirna asked, "Has he come back, Daddy? "

每天晚上，在我到家時，米娜總是要問：“爸爸，它回來了嗎？”

It also means that a test based on miRNA levels might help diagnose pancreatic cancer.

這也意味著基于miRNA水平的檢查可能有助于胰腺癌的診斷。

malignant cell transformation; miRNA;

細(xì)胞惡性轉(zhuǎn)化；