Alcophobin

《英文msh詞典》Alcophobin
[入口詞] Alcophobin
[主題詞] Disulfiram
[藥動學] Enzyme Inhibitors
[英文釋義] A carbamate derivative used as an alcohol deterrent. It is a relatively nontoxic substance when administered alone,but markedly alters the intermediary metabolism of alcohol. When alcohol is ingested after administration of disulfiram,blood acetaldehyde concentrations are increased,followed by flushing,systemic vasodilation,respiratory difficulties,nausea,hypotension,and other symptoms (acetaldehyde syndrome). It acts by inhibiting aldehyde dehydrogenase.