C1q
《英文msh詞典》C1q
[入口詞] C1q
[主題詞] Complement 1q
[英文釋義] Subcomponent of complement 1 (C1) which recognizes and binds to the heavy chain of IMMUNOGLOBULIN G or IMMUNOGLOBULIN M initiating the classical complement pathway. The interaction of C1q and immunoglobulin activates C1r and C1s. The activated C1r and C1s molecules are cleaved off the complex by C1-inhibitor,allowing the collagen-like region of C1q to become accessible for interaction with cell membrane C1q receptors.