《英文msh詞典》Cell,TC1
[入口詞] Cell,TC1
[主題詞] T-Lymphocytes,Cytotoxic
[英文釋義] Immunized T-lymphocytes which can directly destroy appropriate target cells. These cytotoxic lymphocytes may be generated in vitro in mixed lymphocyte cultures (MLC),in vivo during a graft-versus-host (GVH) reaction,or after immunization with an allograft,tumor cell or virally transformed or chemically modified target cell. The lytic phenomenon is sometimes referred to as cell-mediated lympholysis (CML). These CD8-positive cells are distinct from natural killer cells (KILLER CELLS,NATURAL) and from KILLER CELLS mediating antibody-dependent cell cytotoxicity. There are two effector phenotypes: TC1 and TC2.