《英文msh詞典》Klinoril
[入口詞] Klinoril
[主題詞] Sulindac
[藥動(dòng)學(xué)] Cyclooxygenase Inhibitors
[英文釋義] A sulfinylindene derivative prodrug whose sulfinyl moiety is converted in vivo to an active NSAID analgesic. Specifically,the prodrug is converted by liver enzymes to a sulfide which is excreted in the bile and then reabsorbed from the intestine. This helps to maintain constant blood levels with reduced gastrointestinal side effects.