MK-803
《英文MSH詞典》MK-803
[入口詞] MK-803
[主題詞] Lovastatin
[藥動(dòng)學(xué)] Hydroxymethylglutaryl-CoA Reductase Inhibitors
[英文釋義] A fungal metabolite isolated from cultures of Aspergillus terreus. The compound is a potent anticholesteremic agent. It inhibits 3-hydroxy-3-methylglutaryl coenzyme A reductase (HYDROXYMETHYLGLUTARYL COA REDUCTASES),which is the rate-limiting enzyme in cholesterol biosynthesis. It also stimulates the production of low-density lipoprotein receptors in the liver.