Probes,Oligonucleotide

《英文msh詞典》Probes,Oligonucleotide
[入口詞] Probes,Oligonucleotide
[主題詞] Oligonucleotide Probes
[英文釋義] Synthetic or natural oligonucleotides used in hybridization studies in order to identify and study specific nucleic acid fragments,e.g.,DNA segments near or within a specific gene locus or gene. The probe hybridizes with a specific mRNA,if present. Conventional techniques used for testing for the hybridization product include dot blot assays,Southern blot assays,and DNA:RNA hybrid-specific antibody tests. Conventional labels for the probe include the radioisotope labels 32P and 125I and the chemical label biotin.

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