CI898
《英文MSH詞典》CI898
[入口詞] CI898
[主題詞] Trimetrexate
[藥動學(xué)] Folic Acid Antagonists
[英文釋義] A nonclassical folic acid inhibitor through its inhibition of the enzyme dihydrofolate reductase. It is being tested for efficacy as an antineoplastic agent and as an antiparasitic agent against PNEUMOCYSTIS PNEUMONIA in AIDS patients. Myelosuppression is its dose-limiting toxic effect.