Footprinting,DNA

《英文msh詞典》Footprinting,DNA
[入口詞] Footprinting,DNA
[主題詞] DNA Footprinting
[英文釋義] A method for determining the sequence specificity of DNA-binding proteins. DNA footprinting utilizes a DNA damaging agent (either a chemical reagent or a nuclease) which cleaves DNA at every base pair. DNA cleavage is inhibited where the ligand binds to DNA. (from Rieger et al.,Glossary of Genetics: Classical and Molecular,5th ed)