《英文MSH詞典》R-38486
[入口詞] R-38486
[主題詞] Mifepristone
[藥動(dòng)學(xué)] Menstruation-Inducing Agents
[英文釋義] A progestational and glucocorticoid hormone antagonist. Its inhibition of progesterone induces bleeding during the luteal phase and in early pregnancy by releasing endogenous prostaglandins from the endometrium or decidua. As a glucocorticoid receptor antagonist,the drug has been used to treat hypercortisolism in patients with nonpituitary CUSHING SYNDROME.