Sclerosis,Disseminated

《英文msh詞典》Sclerosis,Disseminated
[同義詞] Sclerosis,Disseminated
[主題詞] Multiple Sclerosis
[中文釋義] 硬化,彌漫性
[英文釋義] An autoimmune disorder mainly affecting young adults and characterized by destruction of myelin in the central nervous system. Pathologic findings include multiple sharply demarcated areas of demyelination throughout the white matter of the central nervous system. Clinical manifestations include visual loss,extra-ocular movement disorders,paresthesias,loss of sensation,weakness,dysarthria,spasticity,ataxia,and bladder dysfunction. The usual pattern is one of recurrent attacks followed by partial recovery (see MULTIPLE SCLEROSIS,RELAPSING-RE;MITTING),but acute fulminating and chronic progressive forms (see MULTIPLE SCLEROSIS,CHRONIC PROGRESSIVE) also occur. (Adams et al.,Principles of Neurology,6th ed,p903)