hdac

美 　英

• 網(wǎng)絡(luò)組蛋白去乙酰化酶；組蛋白脫乙酰基酶；組蛋白脫乙酰化酶

例句

In summary, curcumin inhibited the HAT activity and has no effect on HDAC activity in in vitro assays.

以上結(jié)果表明，姜黃素在體外具有HAT抑制活性，而對(duì)HDAC活性無(wú)影響。

However, existing HDAC inhibitors can exhibit low potency, lack of selectivity, and poor pharmacokinetic or toxicity profiles.

但現(xiàn)有HDAC抑制劑效度低、缺乏選擇性、藥代動(dòng)力學(xué)或毒性特征較差。

The object is to find a novel pharmacological activity of a compound capable of inhibiting an HDAC.

本發(fā)明的目的在于發(fā)現(xiàn)具有HDAC抑制作用的化合物的新的藥理作用。

We found that the HDAC inhibitors drastically improved the learning ability of our mouse model.

我們發(fā)現(xiàn)，HDAC抑制劑大大提高了我們的小鼠模型的學(xué)習(xí)能力。

Objective: To improve the synthetic procedure of the histone deacetylase (HDAC) inhibitor SAHA.

目的：改進(jìn)組蛋白去乙酰化酶抑制劑SAHA的合成工藝。

HDAC inhibitors block the removal of these acetyl groups.

HDAC抑制劑阻斷了去乙酰基化過程。

HDAC removes certain chemicals, called acetyl groups, from a wide range of proteins.

HDAC可以從很多蛋白質(zhì)中去除一種叫做乙酰基的化學(xué)結(jié)構(gòu)。

HDAC activity plays a key role in the regulation of gene expression, and HDAC is a clinically validated cancer target.

HDAC活性在基因表達(dá)的調(diào)控中發(fā)揮關(guān)鍵作用，HDAC是一種經(jīng)過臨床驗(yàn)證的癌癥靶標(biāo)。

In addition, the activity of non-histone proteins can be regulated through HDAC-mediated hypo-acetylation.

此外，活動(dòng)的非組蛋白可以調(diào)節(jié)通過HDAC介低乙酰化。

The present invention relates to hydroxamic acid derivatives that are inhibitors of histone deacetylase (HDAC).

本發(fā)明涉及作為組蛋白脫乙酰基酶（HDAC）抑制劑的異羥肟酸衍生物。

The effect of the HDAC inhibitor and the anti-cancer agent may be additive or synergistic.

HDAC抑制劑和抗癌藥的作用可能是加和性或協(xié)同的。

HDAC Heater, Defroster, Air Conditioning Assembly

加熱器，除霜器及空調(diào)總成

Structure based virtual screening of HDAC inhibitors

基于結(jié)構(gòu)的組蛋白去乙酰化酶抑制劑虛擬篩選

Sweatt's lab has already studied a group of experimental drugs called HDAC inhibitors

斯韋特的實(shí)驗(yàn)室已經(jīng)研究了一組叫做HDAC抑制劑的試驗(yàn)性藥物

The role of HDAC 2 in pressure overload-induced cardiac hypertrophy of rat

組蛋白脫乙酰基酶2在大鼠心肌肥大中的作用