methylation
美 [meθ?'le??(?)n] 
英 [meθ?'le??(?)n]
- n.甲基化作用
- 網(wǎng)絡(luò)甲基化酌；甲基化反應(yīng)；甲基化藥物
英漢解釋
例句
Methylation, the addition to a base of a group of three hydrogens and a carbon atom, is one way in which genes are regulated.
甲基化就是在一個(gè)堿基上加上一個(gè)由三個(gè)氫原子和一個(gè)碳原子組成的基團(tuán)。它是一種基因調(diào)整的方式。
Researchers looked for - and found - a chemical change called DNA methylation in healthy tissue adjacent to breast tumors.
研究者尋找并發(fā)現(xiàn)了靠近腫瘤組織的健康組織中有“DNA甲基化”這種化學(xué)改變。
Scientists have several reasons to suspect that this methylation pattern might contribute to autoimmunity .
有數(shù)個(gè)理由使科學(xué)家懷疑，甲基化的模式可能會影響自體免疫。
Consistent with these important roles, a growing number of human diseases have been found to be associated with aberrant DNA methylation.
越來越多的人類疾病被發(fā)現(xiàn)同DNA甲基化的異常有關(guān)。
In malignant cell the pattern of DNA methylation, as well as the set of DNA methyltransferase activities, differs from that in normal cell.
在惡性腫瘤細(xì)胞中，DNA甲基化模式，以及一套DNA甲基轉(zhuǎn)移酶活性不同于正常細(xì)胞。
DNA methylation is one of the most common epigenetic events occurring in human genome and is implicated in cancer.
DNA甲基化是人類基因組發(fā)生最為常見的一種表觀遺傳學(xué)事件，因而研究甲基化與腫瘤的關(guān)系成為當(dāng)前分子生物學(xué)的熱點(diǎn)之一。
METHODS Sugar composition analysis, methylation analysis and NMR were used to determine the structural features.
方法采用糖組成分析、甲基化分析以及NMR確定該多糖的結(jié)構(gòu)。
This results in a considerable reduction in the time required for completion of a detailed genomic methylation project.
這種結(jié)果相當(dāng)大的減少了完成一個(gè)詳細(xì)的基因組甲基化項(xiàng)目所需要的時(shí)間。
Methylation is an epigenetic modification to one's DNA that changes a gene's activity, generally reducing that activity within the genome.
甲基化作用是對DNA的后天修改，并改變基因活動，通常是在基因組內(nèi)減少這個(gè)活動。
It can be thus suggested, that the plant cell contains at least two different, and probably, interdependent systems of DNA methylation.
因此能夠建議，植物細(xì)胞包含至少兩種不同，可能相互依賴的DNA甲基化系統(tǒng)。
In the case of stress, previous studies have suggested that methylation of the gene which encodes glucocorticoid receptors is important.
在“抑郁母親”的案例中，先前的研究提出，以糖皮質(zhì)激素受體編碼的基因的甲基化起到了很重要的最用。
Methylation of cytosine residues is one of the most versatile mechanisms of epigenetic regulation.
胞嘧啶殘基的甲基化是表觀遺傳調(diào)控的最復(fù)雜的機(jī)制之一。
Bisulphite genomic sequencing is a widely used technique for detailed analysis of the methylation status of a region of DNA.
亞硫酸氫鹽基因組測序是詳細(xì)分析一個(gè)區(qū)域的DNA甲基化狀態(tài)的一種廣泛使用的技術(shù)。
The aetiology of RSS is still unclear but it has been correlated with the degrees of gene methylation.
目前，導(dǎo)致RSS的病因仍不明瞭，但近來研究顯示可能與部分基因的甲基化程度有關(guān)。
Whether cytosine methylation is the explanation for this difference has yet to be tested, but something is clearly happening.
胞嘧啶甲基化是否能夠解釋這種差異還有待考察，但是的確是有些什么東西存在著。
DNA methylation is a chemical modification made to DNA that plays an important role in dictating how DNA is read and interpreted by a cell.
DNA甲基化是一個(gè)化學(xué)修飾，它在讓細(xì)胞正確的解讀DNA的過程中起著重要的作用。
The work is one of several clues that DNA methylation affects the formation and maintenance of memories.
這項(xiàng)工作是DNA甲基化影響記憶形成和延續(xù)的線索之一。
One of the best known epigenetic factors is DNA methylation, which is a major mechanism for regulation of gene expression.
表觀因子中最著名的一個(gè)是DNA甲基化，它是基因表達(dá)調(diào)控的一個(gè)主要機(jī)制。
Therefore, profiling DNA methylation across the genome is vital to understanding the influence of epigenetics.
因此，跨基因組的DNA甲基化譜對于理解表觀遺傳學(xué)的影響是極其重要的。
For how the methylation was involved in muscle development and myogenin gene regulation precisely requires further study to prove.
至于甲基化是如何參與肌肉的發(fā)育和肌細(xì)胞生成素基因的精確調(diào)控的尚需進(jìn)一步研究證明。
DNA methylation is an important epigenetic modification which regulates a number of biological processes.
DNA甲基化作為一種重要的表觀遺傳修飾，調(diào)節(jié)著機(jī)體許多生物學(xué)過程。
Malignant gliomas often have the MGMT gene inactivated due to aberrant methylation of its promoter region.
惡性神經(jīng)膠質(zhì)瘤經(jīng)常有MGMT基因被撤消的由于它的促進(jìn)者區(qū)域的出軌甲基化。
Genes suppressed by this methylation include tumor suppressors that would otherwise prevent cancer growth and spread.
被該甲基化抑制的基因包括通過其它方式預(yù)防腫瘤生長與擴(kuò)散的腫瘤抑制基因。
Several epigenetic drugs targeting DNA methylation and histone deacetylation enzymes have been tested in clinical trials.
靶向DNA甲基化和組蛋白去乙酰化酶的幾個(gè)表觀藥物已經(jīng)在臨床試驗(yàn)中被測試。
DNA methylation is one of the most common epigenetic events in eukaryotic cell.
DNA甲基化是真核細(xì)胞基因組最常見的一種表觀遺傳學(xué)修飾。
However, then injecting them with a drug to inhibit methylation seemed to erase any memory of the shock.
然而，在給它們注射了抑制甲基化作用的藥物后，它們對于電擊的記憶似乎就完全被消去了。
The inactivation of antioncogene by methylation has become one of important pathogenesis mechanisms of leukemia.
抑癌基因甲基化失活已成為白血病發(fā)生的重要機(jī)制之一。
Results indicate that the primary productivity is an important indicator of Hg methylation in reservoirs.
以上研究表明，初級生產(chǎn)力水平是水庫汞甲基化的重要影響因素。
The code written on his tones consists of post-translational modifications, including acetylation and methylation.
代碼寫在蛋白包括翻譯后的修改，包括乙酰化和甲基化。
What happens to the unbranched glucose residues in amylopectin during the methylation and hydrolysis procedure?
在甲基化和水解過程中不分支的葡萄糖殘基會發(fā)生什么變化？
In plants, aberrant RNA signals direct DNA methylation to target sequences, sometimes appropriately and sometimes inappropriately.
在植物中，異常RNA信號有時(shí)適當(dāng)的，有時(shí)不適當(dāng)的指導(dǎo)了DNA甲基化成為靶序列。
Aberrant DNA methylation is one of the major characteristics of tumor cells in addition to genetic and other epigenetic alterations.
DNA甲基化的異常是腫瘤細(xì)胞的主要特征之一，此外還有遺傳的和其他表觀上的改變。
Various factors can influence methylation, including environmental conditions.
很多因素都可以影響甲基化，包括環(huán)境條件。
However, there is such a diversity of DNA methylation profiling techniques that it can be challenging to select one.
但是，有如此多種多樣的DNA甲基化譜技術(shù)，選擇其一可能是有挑戰(zhàn)性的。
This methylation is associated with gene silencing, as it causes the DNA's double helix to fold even tighter upon itself.
這個(gè)甲基化作用同基因沉默有關(guān)，因?yàn)?/c>它會導(dǎo)致DNA的雙螺旋折疊得更加緊密。
Replication of methylation patterns by DNA methyltransferases maintains genome stability through cell division.
甲基化作用可以使基因組在細(xì)胞分裂過程中保持穩(wěn)定。
The methylation of histone lysine is an important covalent modification at its tails and plays a key role in epigenetic regulation.
組蛋白賴氨酸甲基化是組蛋白尾段發(fā)生的一種重要共價(jià)修飾，在基因的表觀遺傳轉(zhuǎn)錄調(diào)控中起著關(guān)鍵的作用。
DNA methylation, catalyzed by methyltransferases, is a normal epigenetic DNA modification approach in eukaryotic cells.
DNA甲基化由DNA甲基轉(zhuǎn)移酶催化發(fā)生，是真核細(xì)胞DNA正常的表觀遺傳學(xué)修飾方式。
Here, we review the advances in this field, meanwhile, function of DNA methylation in recombination suppression is being analysed briefly.
本文較全面綜述了這一領(lǐng)域的進(jìn)展，并對DNA甲基化在植物性染色體重組抑制形成過程中可能的作用進(jìn)行了簡要分析。
This study did not reveal the interaction between polymorphism of GSTM1and CYP1A1 gene and methylation of P16 in lung cancer.
GSTM1與CYP1A1基因多態(tài)性與P16基因甲基化之間未發(fā)現(xiàn)明顯的交互作用。
