pharmacophore

pharmacophore

美 　英

• n.藥效基團
• 網絡藥效團；藥效結構；藥效團模型

英漢解釋

n.

1. 藥效基團

例句

The experiment proves that the derivative plays better medicine effect than single pharmacophore.

實驗證明這種衍生物的藥效比單一的藥效基團發揮的更好。

Recent reviews in Drug Discovery Today have concentrated on screening by docking and by pharmacophore searching.

最近的評論今天在藥物發現都集中在篩選對接和藥效搜索。

Moreover, development of pharmacophore point theory greatly increases the effectivity of virtual screening in the database.

而且，藥效團模型理論的發展大大提高了在數據庫中進行虛擬篩選的有效性。

This is because once a pharmacophore is known, medicinal chemists can modify it to reduce toxicity while maintaining (or enhancing) potency.

這是因為一旦知道藥效基因，藥物化學家就可以修飾它，在保持藥效的基礎上減少毒性。

A three-dimensional pharmacophore model of two types of HER2 inhibitors was obtained by using the CATALYST software.

通過CATALYST軟件包得到了兩類HER2抑制的三維藥效團模型。

Using Distance Comparison Method to Build Pharmacophore Model of Epidermal Growth Factor Receptor Inhibitors

距離比較法構建表皮生長因子受體抑制劑的藥效團模型

Constructing the Pharmacophore Models of Tyrosinase Inhibitors by DISCO Method

距離比較法構建酪氨酸酶抑制劑的藥效團模型

Pharmacophore Perception, Development, and Use in Drug Design

藥物設計中的藥效團的感知、開發與應用

Synthesis of Novel Type ALS Inhibitors Based on Pharmacophore Model Design

基于藥效團模型設計合成新型ALS抑制劑