rapamycin
美
英 
- 網(wǎng)絡(luò)雷帕霉素;納巴霉素;雷怕霉素
例句
Rapamycin is a critical-dose drug requiring at least monthly monitoring of drug concentrations in the blood.
雷帕霉素是一種臨界劑量藥物,用藥后至少需要每月監(jiān)測血液中藥物的濃度。
Future studies on rapamycin and mTOR will work backwards from the general effect to specific mechanisms, said Harrison.
Harrison提出未來關(guān)于雷帕霉素和mTOR的研究將從其一般影響轉(zhuǎn)為特定機制。
the effects of rapamycin as a pharmacological preconditioning agent during IR on the severity of injury in vitro have been studied.
想表達(dá)的中文意思:很少有研究探討雷帕霉素作為一種預(yù)適應(yīng)藥物在在體缺血再灌注中的作用。
The fact that rapamycin is already clinically approved for other uses will facilitate future clinical trials of the drug.
實際上,瑞帕霉素已被批準(zhǔn)臨床用于其他用途,這將有助與將來該藥地臨床驗證。
Previous research on rapamycin has hinted that it may have the power to extend human lifespan by more than a decade.
以前對雷帕霉素的研究為其也許可以把人的壽命延長十幾歲提供了線索。
However, because rapamycin depresses the immune system, it would have serious side effects for people with Parkinson's.
即便如此,因為雷帕霉素抑制了免疫系統(tǒng),它對帕金森癥患者有負(fù)面作用。
Pharmaceutical companies would also be wise to hunt for drugs that act on the same biological pathway as rapamycin.
制藥公司也會明智地去尋找與一些藥物,這些藥物作用與雷帕霉素所作用的生物途徑相同。
Figure 1: A plaque on Easter Island commemorating the discovery of a bacterium producing rapamycin, a potent immunosuppressant.
圖1:復(fù)活節(jié)島上的銘牌,紀(jì)念一種能產(chǎn)生抗免疫物質(zhì)——納巴霉素的發(fā)現(xiàn)。
But the new finding by Strong and his colleagues "more clearly identifies the [target of rapamycin] pathway as important across species. "
斯特朗及其同事最近發(fā)現(xiàn),更多的人清楚認(rèn)為雷帕霉素靶蛋白通道在各個物種間間重要性。
Healthy ageing will also be the metric by which medicines like rapamycin are tested against in humans, says Kaeberlein.
健康的變老將是一些用在人類身上試驗的,類似雷帕霉素藥物的尺度,Kaeberlein說到。
The potent immunosuppressive action of rapamycin is commonly ascribed to inhibition of growth factor-induced T cell proliferation.
強效免疫抑制劑雷帕行動普遍歸因于抑制生長因子誘導(dǎo)T細(xì)胞增殖。
Dr Harrison and his colleagues picked a different molecule that has been seen to work on invertebrates: rapamycin.
Harrison博士及其同事則選擇了另一種對無脊椎動物有效的分子:雷帕霉素。
A novel, simple and cost effective assay for monitoring blood levels of rapamycin (sirolimus) and rapamycin analogues was developed.
我們開發(fā)了一項用于檢測血液中雷帕霉素(西羅莫司)和雷帕霉素類似物濃度的簡便、經(jīng)濟(jì)節(jié)省的新型分析方法。
But rapamycin, a fungus-fighting bacterial secretion originally discovered in the soil of Easter Island, showed a marked effect.
但是,雷帕霉素的作用卻非常明顯。雷帕霉素最初由在智利復(fù)活節(jié)島(EasterIsland)土壤中發(fā)現(xiàn)的一種微生物制成。
Rapamycin is a bacterial product originally found in a soil sample from Easter Island.
雷帕霉素是一種最初發(fā)現(xiàn)于來自復(fù)活節(jié)島土壤樣本中細(xì)菌的制品。
It's unclear whether these problems would counteract any longevity benefit that rapamycin might provide in humans.
尚不清楚,這些問題是否會抵制雷帕霉素可能提供延長生命的益處。
The most commonly used anti-proliferative drugs are paclitaxel and rapamycin, and their derivatives.
目前最常用的抗增生藥物為紫杉醇和雷帕霉素及其衍生物。
Rapamycin suppresses the immune system and carries strong warnings about the resulting risk of infections and death.
雷帕霉素會抑制免疫系統(tǒng)的活動,可能因此造成感染和死亡的風(fēng)險,在這方面已經(jīng)有過嚴(yán)重的前車之鑒。
Rapamycin is known as a kind of macrolide antibiotics.
雷帕霉素是一種大環(huán)內(nèi)酯類抗生素。
That ability also made rapamycin a candidate for research into the mechanisms of aging.
這種能力也使雷帕霉素成為了研究衰老機制的候選者。
Earlier human trials have shown, however, that rapamycin can have serious side effects.
但是,早些時候的人體試驗顯示,雷帕霉素有很嚴(yán)重的副作用。
Bency: In contrast to control group, however, only those groups that rapamycin was given before ischemia can reduce infarct area.
想表達(dá)的中文意思:只有那些在缺血前使用雷帕霉素的實驗組可以減少梗死面積。
Methods Rapamycin was selected to replace previous basic immunosuppressive drugs for the treatment of 7 cases resistant extensive cGVHD.
方法采用雷帕霉素代替前期基礎(chǔ)免疫抑制劑治療難治性廣泛型慢性移植物抗宿主病7例。
More than 1, 900 mice, their total genetic variation roughly comparable to that found in humans, were fed rapamycin.
超過1900只小鼠被給予了雷帕霉素,他們的基因多樣化基本與人類相似。
Several researchers, and the editorial in Nature, cautioned people about taking rapamycin, which is available only by prescription.
一些研究人員以及《自然》雜志的編輯警告人們不要隨便服用雷帕霉素。
The drug, called rapamycin, was originally found in bacteria from Easter Island.
這種叫雷帕霉素的藥最先是在復(fù)活節(jié)島的一種細(xì)菌中找到的。
Conclusion Regimen and dosage of rapamycin in this study were safe to patients and very good response is observed.
結(jié)論雷帕霉素治療方案及該藥物劑量對患者較為安全,且觀察到非常好的治療反應(yīng)。
Rapamycin is not perfect, however.
但是,雷帕霉素并不理想。
When tested on nine-month-old mice, rapamycin had little effect.
當(dāng)在九月大的小鼠上試驗時,雷帕霉素的作用很小。
This drug, rapamycin, was originally discovered in the 1970s in soil from Easter Island.
這一藥物,瑞帕霉素,最初是在1970年復(fù)活節(jié)島土壤中被發(fā)現(xiàn)的。
Conclution: Rapamycin inhibited the proliferation of leukemia HL-60 cells dependent on density and time.
結(jié)論:雷帕霉素具有濃度和時間依賴性抑制白血病細(xì)胞HL-60增殖。
Methods: The inhibitation of HL-60 cells by Rapamycin was measured by MTT assay.
方法:用MTT比色法測定雷帕霉素對HL-60細(xì)胞增殖的影響;
The macrolide rapamycin is used clinically to treat graft rejection and restenosis.
雷帕霉素的大環(huán)內(nèi)酯類用于臨床治療移植排斥和狹窄。
That is not to recommend people take doses of rapamycin.
這并不是鼓勵人們食用納巴霉素。
Rapamycin-eluting stents for the treatment of bifurcated coronary lesions: A randomized comparison of a simple versus complex st
下一篇文章:應(yīng)用雷帕霉素涂層支架治療分支冠脈病變:隨機比較簡化治療方案和復(fù)雜治療方案
Clinical result of Rapamycin eluting stent implanting in the patients with coronary heart disease combined with diabetes
雷帕霉素洗脫支架在合并糖尿病的冠心病患者介入治療中的臨床應(yīng)用
Experimental studies of rapamycin eye drops on the prevention of penetrating keratoplasty rejection in a rat model
雷帕霉素滴眼液抑制大鼠角膜移植的免疫排斥反應(yīng)
Sustained rapamycin drug delivery system in prevention of high risk corneal allograft rejection and neovascularization in rabbits
雷帕霉素緩釋片防治兔高危角膜移植免疫排斥反應(yīng)和新生血管增殖的研究
A Randomized Comparison Between Paclitaxel-Eluting Stents and Rapamycin-Eluting Stents for Patients With Coronary Artery Diseases
冠心病患者應(yīng)用紫杉醇與國產(chǎn)雷帕霉素洗脫支架的隨機對照研究
Experimental study on rapamycin-batroxobin eluting stent and its prevention of coronary restenosis after angiophaty
雷帕霉素-巴曲酶復(fù)合藥物涂層支架預(yù)防支架內(nèi)再狹窄的實驗研究