Idiotypes,Immunoglobulin

《英文msh詞典》Idiotypes,Immunoglobulin
[同義詞] Idiotypes,Immunoglobulin
[主題詞] Immunoglobulin Idiotypes
[中文釋義] 個體基因型,免疫球蛋白
[英文釋義] Unique,genetically controlled determinants present on ANTIBODIES whose specificity is limited to a single group of proteins (e.g.,another antibody molecule or an individual myeloma protein). The idiotype appears to represent the antigenicity of the antigen-binding site of the antibody and to be genetically codetermined with it. The idiotypic determinants have been precisely located to the IMMUNOGLOBULIN VARIABLE REGION of both immunoglobin polypeptide chains.