Mice,SCID

《英文msh詞典》Mice,SCID
[主題詞] Mice,SCID
[同義詞] SCID Mice
[同義詞] SCID-hu Mice
[同義詞] Severe Combined Immunodeficient Mice
[入口詞] Immunodeficient Mice,Severe Combined
[入口詞] Mouse,SCID
[入口詞] Mouse,SCID-hu
[入口詞] Mice,SCID-hu
[入口詞] Mouse,SCID hu
[入口詞] SCID Mouse
[入口詞] SCID hu Mice
[入口詞] SCID-hu Mouse
[中文釋義] 小鼠,SCID
[英文釋義] Mice homozygous for the mutant autosomal recessive gene scid which is located on the centromeric end of chromosome 16. These mice lack mature,functional lymphocytes and are thus highly susceptible to lethal opportunistic infections if not chronically treated with antibiotics. The lack of B- and T-cell immunity resembles severe combined immunodeficiency (SCID) syndrome in human infants. SCID mice are useful as animal models since they are receptive to implantation of a human immune system producing SCID-human (SCID-hu) hematochimeric mice.