oligonucleotides
美 [?l?ɡ?n'juklio?ta?dz]
英 [?l?ɡ?n'ju:kli:??ta?dz] 
- n.寡核苷酸;低核苷酸;低聚核苷酸;寡聚核苷酸
- 網(wǎng)絡(luò)寡核甘酸;寡核酸;寡核苷酸類
詞形變化
復(fù)數(shù):oligonucleotides
英漢解釋
英英解釋
例句
The mechanism, classification and characteristics of antisense oligonucleotides and its application in relative fields are reviewed.
簡述了反義技術(shù)的理論機(jī)制、反義核酸的種類、應(yīng)具備的特性及在相關(guān)領(lǐng)域中的應(yīng)用。
The immunostimulatory oligonucleotides of the invention preferably comprise novel purines.
本發(fā)明的免疫刺激性寡核苷酸優(yōu)選的包括新嘌呤。
Important new applications that could not be performed using natural oligonucleotides have emerged.
許多重要的、用天然寡核苷酸無法實(shí)現(xiàn)的新應(yīng)用也應(yīng)運(yùn)而生。
The suppliers then combined subsets of oligonucleotides to produce the requested cassettes .
供應(yīng)者結(jié)合子寡核苷酸來生產(chǎn)所需要的盒。
As compared to conventional drugs that work on proteins, antisense oligonucleotides work on RNA.
與傳統(tǒng)的作用于蛋白質(zhì)的藥物相比,反義寡聚核苷酸作用于RNA。
The present invention relates to regulate activity of target RNA oligonucleotides.
本發(fā)明涉及用于調(diào)節(jié)靶RNA活性的寡核苷酸。
The invention relates to the therapeutic use of oligonucleotides as immunostimulatory agents in immunotherapy applications.
本發(fā)明涉及作為免疫刺激劑的寡核苷酸在免疫治療應(yīng)用中的治療用途。
It is especially critical when labeling oligonucleotides, since even using pure dye results in multiple oligo conformers (6).
尤其是在標(biāo)記寡聚核苷酸,即使是用純的染料也會出現(xiàn)多個寡異構(gòu)體。
However, many classes of oligonucleotides are polyanions, so they cannot cross over cell membrane.
但是,大多數(shù)此類化合物是呈負(fù)電性的,不能有效跨越細(xì)胞膜。
Suppose you are working with oligonucleotides 32 nucleotides in length.
假設(shè)你在用32核苷酸長度的寡核苷酸工作。
Objective To study inhibition of VEGF expression in human bladder carcinoma cells by antisense oligonucleotides.
目的觀察VEGF反義寡核苷酸對膀胱癌細(xì)胞VEGF表達(dá)的抑制情況。
Immobilization of Oligonucleotides on Photolithographic Gold Films and Its Analytical Applications
寡核苷酸在石英金膜表面的固定及其分析性能
Study of iodine labeling bcl-2 antisense oligonucleotides and the evaluation of its stability and biodistribution
碘標(biāo)記bcl-2反義寡核苷酸的研究及其穩(wěn)定性與生物分布的評價
Preparation of cationic liposomes and its role in enhancing cellular uptake of antisense oligonucleotides
反義寡核苷酸陽離子脂質(zhì)體的制備和體外細(xì)胞攝取研究
Application of Antisense Oligonucleotides Designed to Screened Green Fluorescence Protein mRNA Accessible Sites
綠色熒光蛋白基因mRNA反義寡核苷酸的篩選和應(yīng)用
Study on the transfection mechanism of cationic fusogenic liposomes for antisense oligonucleotides and its role in protection against DNase
陽離子膜融合脂質(zhì)體的細(xì)胞轉(zhuǎn)染機(jī)制及其保護(hù)作用
Effect of antisense oligonucleotides encoding telomerase reverse transcriptase on thyroid carcinoma cell apoptosis
端粒酶逆轉(zhuǎn)錄酶反義寡核苷酸對甲狀腺癌細(xì)胞凋亡的影響
Inhibiting proliferation of cultured rat lens epithelial cells by bFGF antisense oligonucleotides and their liposomes
堿性成纖維細(xì)胞生長因子反義寡核苷酸及其脂質(zhì)體對體外培養(yǎng)的大鼠晶狀體上皮細(xì)胞增殖的抑制作用
The inhibitory effect of vascular endothelial growth factor antisense oligonucleotides in angiogenesis of thyroid carcinoma
血管內(nèi)皮生長因子反義寡核苷酸抑制甲狀腺癌血管生成的效應(yīng)
Observation on distribution and stability of C-myc mediated by liposome antisense oligonucleotides in retinal pigment epithelium cell
脂質(zhì)體介導(dǎo)的C-myc反義寡核苷酸在視網(wǎng)膜色素上皮細(xì)胞中分布和穩(wěn)定性的觀察
Ultrasound Activation of Liposome Microbubbles Enhances the Transfer of Antisense Oligonucleotides in Vitro
超聲空化脂質(zhì)體微氣泡促反義寡核苷酸轉(zhuǎn)染的體外實(shí)驗研究
The Application of Chemically Modified Nucleotides on Antisense Oligonucleotides and Nucleic Acid Catalysts
化學(xué)修飾在反義寡核苷酸和核酸催化劑的應(yīng)用
Inhibitory effect of vascular endothelial growth factor antisense oligonucleotides on human osteosarcoma cells
血管內(nèi)皮生長因子反義寡核苷酸對骨肉瘤細(xì)胞的抑制作用
Inhibitory effects of antisense oligonucleotides on VEGF gene expression by human hepatocellular carcinoma cells
反義寡核苷酸抑制肝癌血管內(nèi)皮生長因子表達(dá)
Effects of heparanase antisense oligonucleotides on VEGF protein expression in the transplanted esophageal cancer tissue of nude mice
乙酰肝素酶反義寡核苷酸對裸鼠食管癌移植瘤組織中VEGF蛋白表達(dá)的影響
Influence of antisense oligonucleotides encoding TERT mRNA to gene expression and proliferation of thyroid carcinoma cells
端粒酶逆轉(zhuǎn)錄酶反義寡核苷酸對甲狀腺癌細(xì)胞增殖的影響
Application of Separation and Analysis Techniques for Antisense Oligonucleotides
反義寡核苷酸藥物分離分析技術(shù)的應(yīng)用研究
The Aptamer Handbook: Functional Oligonucleotides and Their Applications
相似法則手冊:低核苷酸原理及其應(yīng)用
Inhibition of telomerase antisense oligonucleotides on telomerase activity of cervical carcinoma cell in vitro
端粒酶反義寡核苷酸體外抑制宮頸癌細(xì)胞端粒酶活性的研究
Allyl as a Protective Group for the Synthesis of Modified Oligonucleotides
烯丙基作為保護(hù)基在修飾寡核苷酸合成中的應(yīng)用
Telomerase RNA antisense oligonucleotides inhibit growth of human choriocarcinoma xenograft in nude mice
端粒酶RNA反義寡核苷酸對人絨毛膜癌裸鼠移植瘤的生長抑制作用
Inhibition of the Expression of E-selectin and Intercellular Adhesion Molecule-1 in Endothelial Cells by Antisense Oligonucleotides
反義寡核苷酸對內(nèi)皮細(xì)胞E選擇素和胞間粘附分子1表達(dá)的抑制作用
Progress of Chemical Modifications of Antisense Oligonucleotides
反義寡核苷酸的化學(xué)修飾
Antisense oligonucleotides targeting XIAP induces the apoptosis of malignant glioma cells
XIAP反義寡核苷酸抑制膠質(zhì)瘤細(xì)胞增殖和誘導(dǎo)凋亡的體外實(shí)驗研究
Effect of Telomerase Antisense Oligonucleotides on Inhibiting Growth of Hepatocarcinoma Cell
端粒酶反義寡核苷酸對肝癌細(xì)胞生長抑制作用
Inhibition of glioma growth by vascular endothelial growth factor antisense oligonucleotides in rats
血管內(nèi)皮生長因子反義寡核苷酸抑制大鼠腦膠質(zhì)瘤生長
Effect of Telomerase Antisense Oligonucleotides on the Inhibition of Telomerase Activity and Cell Growth in Bladder Cancer in Vitro
端粒酶反義寡核苷酸對膀胱癌端粒酶活性及細(xì)胞增殖的影響
Enhanced Growth Inhibition Effect of Antisense Oligonucleotides Mediated by Cationic Liposomes on HeLa Cells
陽離子脂質(zhì)體介導(dǎo)端粒酶反義寡核苷酸促進(jìn)對HeLa細(xì)胞生長的抑制作用
Research progress on immunoregulatory activity of CpG oligonucleotides in primates
CpG寡聚脫氧核苷酸在靈長類動物中免疫調(diào)節(jié)活性的研究進(jìn)展
Inhibitory effect of antisense oligonucleotides on EGFR mRNA and protein expression of retinal pigment epithelial cell in vivo
反義寡核苷酸對人視網(wǎng)膜色素上皮細(xì)胞EGFR表達(dá)的影響