TNF

美 　英

• 網(wǎng)絡(luò)腫瘤壞死因子(tumor necrosis factor)；細(xì)胞因子如腫瘤壞死因子；腫瘤壞死因數(shù)(Tumour Necrosis Factor)

例句

The FDA also reviewed 69 cases of psoriasis and said it found a possible link between the skin disorder and use of TNF blockers.

FDA也檢查了69例牛皮癬，稱皮膚病癥和TNF拮抗劑之間可能存在某種的聯(lián)系。

B cell activating factor (BAFF) is one of the TNF family member, regulates the survival and maturation of B lymphocyte.

B細(xì)胞激活因子（BAFF）是調(diào)節(jié)B淋巴細(xì)胞存活和成熟的細(xì)胞因子，屬于TNF家族成員。

And one of the things were looking at is specific phosphodiesterase inhibitors to block the endotoxin or LPS-stimulable TNF.

目前正在做的一項工作是用特異性磷酸二酯酶抑制劑來阻斷內(nèi)毒素或LPS脂多糖刺激TNF的產(chǎn)生。

The FDA said it had reviewed 147 reports of leukemia in adults and children using TNF blockers, including 30 deaths.

FDA稱已經(jīng)檢查了147例成年和兒童使用TNF拮抗劑的白血病報告，其中30例死亡。

The second report links susceptibility to SLE with increased expression of a gene in the tumor necrosis factor (TNF) superfamily .

第二項報告將SLE易感性與腫瘤壞死因子（TNF）超家族基因的過分表達(dá)聯(lián)系起來。

These cells are activated by a chemical compound called tumor necrosis factor (TNF) released by the neutrophils.

這兩種細(xì)胞能被一種由嗜中性粒細(xì)胞釋放的名為腫瘤壞死因子（TNF）的化合物激活。

Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is a member of the tumor necrosis factor (TNF) superfamily .

TRAIL是腫瘤壞死因子超家族成員，廣泛表達(dá)于多種組織細(xì)胞。

Patients who develop a fungal infection may be advised to stop the TNF blocker until they recover.

受到真菌感染的患者可能會被建議在真菌疾病康復(fù)前中止使用TNF阻滯劑。

TNFR-specific effects in HF should be considered when therapeutic anti-TNF strategies are developed.

開發(fā)抗TNF的治療策略時需要考慮HF過程中TNFR-特異性的作用。

The FDA also has received reports of cases of coccidioidomycosis and blastomycosis, including deaths, in patients treated with TNF blockers.

還收到一些使用TNF阻滯劑導(dǎo)致球孢子病和芽生菌病的報告，甚至還有死亡病例。

Patients taking TNF blockers should be aware that they are more susceptible to serious fungal infections.

使用TNF阻滯劑的患者應(yīng)該注意到他們更易受到嚴(yán)重的真菌感染。

In this chapter, we give an introduction to the different TNF antagonists, with the main focus on therapy management and safety issues.

在這一章中，我們向大家介紹不同的腫瘤壞死因子拮抗劑，對治療與管理和安全問題的主要焦點。

Among the three anti-TNF-alpha agents, this phenomenon has been studied mainly in patients using infliximab, especially in RA and CD.

在三種TNF拮抗劑中，免疫原性相關(guān)研究主要見于英夫利昔治療的病人中，尤其是RA和CD。

Remicade belongs to a class of drugs called tumor necrosis factor (TNF) blockers.

Remicade屬于被稱為腫瘤壞死因子（TNF）阻斷劑類藥物。

Cathepsin B actively participates in hepatocellular apoptosis, e. g. after exposure of hepatocytes to TNF .

組織蛋白酶B積極參與肝細(xì)胞凋亡，肝細(xì)胞后，腫瘤壞死因子，例如接觸。

Results. Typical apoptotic changes of the cell nuclei were observed in the DRG after application of TNF.

結(jié)果：應(yīng)用TNF后，我們觀察到在DGR內(nèi)髓核細(xì)胞典型的調(diào)亡改變。

Overproduction of a cellular messenger called TNF (tumor necrosis factor) is believed to play a role in psoriasis.

生產(chǎn)過剩的一種細(xì)胞信使稱為腫瘤壞死因子（腫瘤壞死因子），相信應(yīng)發(fā)揮自己的作用牛皮癬。

Research Design and Methods: RIP-TNF-NOD mice were crossed to B cell deficient NOD mice and diabetes development monitored.

設(shè)計及方法：RIP-TNF-NOD小鼠與B細(xì)胞缺陷非肥胖糖尿病（NOD）小鼠交配獲得子代，并且監(jiān)測糖尿病病程發(fā)展。

The scientists showed that all three drugs inhibited the production of TNF, which reduced inflammation in these cells.

科學(xué)家們發(fā)現(xiàn)，所有這三種藥物都能抑制TNF的產(chǎn)生，減輕這些細(xì)胞的炎癥情況。

Death receptors belong to the tumour necrosis factor (TNF) receptor superfamily.

死亡受體屬于腫瘤壞死因子（TNF）受體超家族。

thus , we also investigated the effects of elf - mf exposure on clustering of egf , tnf receptors in cultured cells.

因此本文又進(jìn)一步探索了極低頻磁場對細(xì)胞膜受體聚簇的作用。

inflammatory and remodeling responses in HF that are TNF-receptor (TNFR) specific.

導(dǎo)心肌炎癥和重塑反應(yīng)，這些反應(yīng)具有TNF受體（TNFR）特異性。

Immunosuppressive drug addiction can reduce the induction of anti-TNF-alpha antibodies.

加用免疫抑制劑可以減少抗TNF拮抗劑抗體的產(chǎn)生。

Objective: To explore the changes of thyroid hormone and tumor necrosis factor(TNF) in severe patients.

目的：探討危重患者甲狀腺激素與腫瘤壞死因子的動態(tài)變化。

We identified the generation of amino-terminally truncated versions of DBC-1 during tumor necrosis factor (TNF)--mediated apoptosis.

研究者證實，在腫瘤壞死因子（TNF）介導(dǎo)的凋亡過程中，出現(xiàn)DBC-1的氨基端截斷倒位的形成。

Conclusion: TNF may play an promoting role in eccentric left ventricular hypertrophy.

結(jié)論：TNF促進(jìn)了左室構(gòu)型向離心性肥厚的發(fā)展。

Expression of TNF-[alpha] was compared in rats with crush injury, with and without sympathectomy.

比較受擠壓傷的大鼠在接受和不接受交感神經(jīng)切除時TNF-α的表達(dá)情況。

Etanercept is a recombinant soluble TNF-alpha receptor fusion protein that binds to TNF-alpha.

依那西普是一個重組可溶性腫瘤壞死因子-α受體融合蛋白，它可結(jié)合腫瘤壞死因子-α。

Conclusions There is some evidence, albeit incomplete, that combination therapy using TNF-inhibitors is most effective.

結(jié)論那里是一些證據(jù)，雖然殘缺不全，組合療法使用TNF抗化劑是最有效的。

There are now a few uncontrolled studies supporting the use of TNF inhibitors in patients with active disease.

目前，已有幾個無對照組的臨床研究支持使用TNF抑制劑治療活動性病人。

Now that links between inflammation and cancer are appreciated, is TNF a target or a therapeutic in malignant disease -- or both?

現(xiàn)在，鏈接炎癥和癌癥之間的贊賞，是腫瘤壞死因子的目標(biāo)或一種治療惡性疾病-或兩者？

These results suggested that the TNF played an important role in the pathogenesis of MWA.

認(rèn)為TNF在偏頭痛的發(fā)病中起重要作用。

Unfortunately in humans, wiping out all the TNF is not good, which is what Etanercept does.

然而在人類，用依那西普阻斷所有的TNF產(chǎn)生并非是件好事。

Editorial: Anti-TNF Treatment in Crohns Disease: TowardTailored Therapy?

評論：克羅恩病抗腫瘤壞死因子醫(yī)治：趨于集體化醫(yī)治？

But does anti-TNF therapy do anything to reduce the incidence or severity of ankylosis?

但是抗腫瘤壞死因子治療確實能降低關(guān)節(jié)炎的發(fā)生率和嚴(yán)重性么？

RESULTS Ning Zhi Ai can increase their NK activity and decrease their TNF activity.

結(jié)果蛭癌寧可提高病人NK細(xì)胞活性，降低TNF活性。

TNF Antagonists Reduce Cardiovascular Deaths in Rh.

TNF拮抗劑能夠降低類風(fēng)濕關(guān)節(jié)炎患者的心血管死亡率。

The presence of single-stranded DNA, Caspase 3, and TNF further confirmed the occurrence of DRG cell apoptosis.

單鏈DNA、半胱天冬酶3以及TNF的表達(dá)更進(jìn)一步證實了DRG細(xì)胞調(diào)亡的存在。

The injectable drugs suppress the immune system by blocking the activity of TNF, a chemical that can cause inflammation.

注射用藥物通過阻斷腫瘤壞死因子（一種可以引起炎癥的化學(xué)物質(zhì)）的活性來抑制機(jī)體的免疫系統(tǒng)。

Conclusions: RDQ has the inhibitory effect on the production of TNF induced by endotoxin.

結(jié)論：熱毒清對內(nèi)毒素誘生TNF具有抑制作用。