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Receptor,HGF

《英文msh詞典》Receptor,HGF
[入口詞] Receptor,HGF
[主題詞] Proto-Oncogene Protein c-met
[英文釋義] A cell surface protein-tyrosine kinase receptor for HEPATOCYTE GROWTH FACTOR. It consists of an extracellular alpha chain which is disulfide-linked to the transmembrane beta chain. The cytoplasmic portion contains the catalytic domain and critical sites for the regulation of kinase activity. Mutations of the gene for PROTO-ONCOGENE PROTEIN C-MET are associated with papillary renal carcinoma and other neoplasia.