TIMP-2

《英文MSH詞典》TIMP-2
[同義詞] TIMP-2
[主題詞] Tissue Inhibitor-of Metalloproteinase-2
[藥動學] Protease Inhibitors
[英文釋義] A member of the family of TISSUE INHIBITOR OF METALLOPROTEINASES. It is a 21 kD nonglycosylated protein found in tissue fluid and is secreted as a complex with progelatinase A by human fibroblast and uncomplexed from alveolar macrophages. An overexpression of TIMP-2 has been shown to inhibit invasive and metastatic activity of tumor cells and decrease tumor growth in vivo.

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