kinase
美 [?e?z] 
英 ['k?ne?s]
- n.【生化】激酶
- 網(wǎng)絡(luò)蛋白質(zhì)激酶；磷酸化酵素；磷酸激酶
英漢解釋
英英解釋
例句
HHMI researchers have now learned that this pairing causes a physical change in the shape of the kinase domain.
霍華德?休斯醫(yī)學(xué)研究所的研究人員現(xiàn)已經(jīng)得知，這種配對導(dǎo)致了激酶結(jié)構(gòu)域形狀上的物理變化。
This Review provides a broad overview of some of the approaches currently used to discover and characterize new kinase inhibitors.
本次審查提供了一個廣泛的概述了一些目前使用的方法和特點，發(fā)現(xiàn)新的激酶抑制劑。
The peptide can be directed to any region of the protein kinase C isozyme, and in one embodiment, is directed to the V5 domain.
所述肽可以針對蛋白激酶C同工酶的任何區(qū)域，并且在一個實施方案中，針對V5結(jié)構(gòu)域。
Genistein, the tyrosine kinase inhibitors, plays the effect by an inhibition of tyrosine phosphorylation.
Genistein是酪氨酸激酶的非特異性抑制劑，通過抑制酪氨酸的磷酸化而發(fā)揮作用。
The Singaporeans' kinase (win at all costs) negotiating style does them few favours in a region where saving face is important.
新加坡人那種“怕輸”（為了達到目的而不擇手段）的談判方式使得他們幾乎沒有什么朋友。
When wheat plants allowed to become deficient in potassium, pyruvate kinase activity increased.
當(dāng)小麥植株令其缺鉀時，丙酮酸激酶活性隨之升高。
Rudolph initially knew the kinase's and phosphatase's general topographies as well as the locations of their active sites.
Rudolph起初知道激酶和磷酸酶總拓樸圖以及活性位點的位置。
Objective To investigate the expression of focal adhesion kinase in peripheral blood of colorectal cancer and its clinical significance.
目的探討大腸癌患者外周血淋巴細(xì)胞粘著斑激酶的表達及其臨床意義。
KIT protein is expressed in SCLC, and its kinase activity has been implicated in the pathophysiology of many tumours, including SCLC.
KIT蛋白在小細(xì)胞肺癌中表達，它的激酶活性與許多腫瘤的病理生理學(xué)都有聯(lián)系，包括小細(xì)胞肺癌。
The glucose role is independent and thus unaffected by turning off the kinase-activated growth signals, the researchers found.
研究者們發(fā)現(xiàn)，葡萄糖的作用是獨立的，因此關(guān)閉酪氨酸激酶激活的生長信號通路并不會對葡萄糖產(chǎn)生影響。
If STI571 inhibits the BCR-ABL kinase so effectively, what is the result of its inhibition of the ABL kinase in normal cells?
如果STI571可高效地抑制BCR-ABL激酶活性，那它對正常細(xì)胞的ABL激酶的抑制會產(chǎn)生什么結(jié)果呢？
Protein kinase C(PKC) is the main signaling molecule of the diacylglycerol dependent protein kinase C signal transducing system.
蛋白激酶C（PKC）是甘油二酯依賴的PKC信號轉(zhuǎn)導(dǎo)系統(tǒng)的主要信號分子。
Focal-adhesion kinase (FAK) is an important mediator of growth-factor signalling, cell proliferation, cell survival and cell migration.
焦點粘附激酶（斑）是一個重要的調(diào)停人的生長因子信號，細(xì)胞增殖，細(xì)胞存活和細(xì)胞遷移。
In the first set of experiments, the researchers demonstrated that the kinase domain of EGFR is normally maintained in the off state.
在試驗的第一階段，研究者證明，EGFR的激酶結(jié)構(gòu)域在通常情況下處于關(guān)閉的狀態(tài)。
The protein, known as AMP-activated protein kinase or AMPK, controls metabolic decisions of cells.
這種蛋白即是AMP活化蛋白激酶（AMPK），它控制著細(xì)胞能量代謝的關(guān)鍵。
Isoflavone . Inhibitor of EGFR tyrosine kinase, blocking phosphatidylinositol turnover.
異黃酮類。抑制EGFR酪氨酸激酶。阻斷磷脂酰肌糖的翻轉(zhuǎn)。
Objective To investigate the change of serum creatine kinase (CK) level and its clinical significance in acute urticaria.
目的探討急性蕁麻疹患者血清肌酸激酶水平的變化及其臨床意義。
The extracellular signal-regulated kinase(ERK) is an important member of mitogen-activated protein kinase(MAPK) family.
細(xì)胞外信號調(diào)節(jié)激酶是絲裂原激活蛋白激酶家族的重要成員。
The insulin may suppress the protein kinase directly, the promotion activation glycogen enzyme production, increases the glycogen synthesis.
胰島素可直接抑制蛋白激酶，促進活化型糖原合成酶的生成，增加糖原合成。
Heart rate, serum creatine kinase, testosterone, cortisol, blood urea, glutamine etc serve as markers for the diagnosis of overtraining.
診斷過度訓(xùn)練的常用指標(biāo)有心率、肌酸激酶、血睪酮、血尿素、血乳酸、谷氨酰胺等。
They did this by engineering a virus to express the gene for the kinase, and then infected specific areas of the brain involved in memory.
他們的制作方法如下：首先制造一種病毒來表達該激酶的基因，之后感染和目標(biāo)記憶相關(guān)聯(lián)的大腦區(qū)域。
Polyadenylation is mediated by the phosphorylation of CPEB by Aurora, a kinase whose activity oscillates with the cell cycle.
是介導(dǎo)的多聚磷酸化CPEB的極光，一個激酶的活動振蕩與細(xì)胞周期。
The invention provides methods for the treatment of tyrosine kinase inhibitor resistant cancers with anti-EGFR antibodies.
本發(fā)明提供了使用抗EGFR抗體治療抗酪氨酸激酶抑制劑的癌癥的方法。
But laboratory experiments suggest mutation slows the activity of a protein called casein kinase I delta (CKIdelta).
實驗室的研究結(jié)果顯示，這種突變使一種名為CKIdelta的蛋白質(zhì)活性變差。
Mutations in GNA11 induced spontaneously metastasizing tumors in a mouse model and activated the mitogen-activated protein kinase pathway.
在小鼠模型中，GNA11突變誘導(dǎo)了自發(fā)轉(zhuǎn)移性腫瘤，激活了絲裂原活化蛋白激酶途徑。
Protein tyrosine kinase(PTK) inhibitor is one of the new targets of oncotherapy.
蛋白酪氨酸激酶（PTK）受體是腫瘤治療的一個新靶點。
BACKGROUND: Fms-like tyrosine kinase-3 (FLT3) gene is one of the receptors for growth factors in early hematogenesis.
背景：Flt3基因是近年來發(fā)現(xiàn)的早期造血生長因子受體基因。
Displays cytostatic and cytotoxic activity. Inhibitor of EGFR kinase. Shows antiangiogenic activity.
顯示細(xì)胞生長抑制和細(xì)胞毒活性。EGFR激酶抑制劑。有抗血管生成活性。
OBJECTIVE The antidiabetic properties of metformin are mediated through its ability to activate the AMP-activated protein kinase (AMPK).
目的二甲雙胍通過激活腺苷酸活化蛋白激酶（AMPK）起到治療糖尿病的作用。
Treatment with Tyrosine Kinase Inhibitors for Patients with Differentiated Thyroid Cancer: the M. D. Anderson Experience.
大量的臨床經(jīng)驗：酪氨酸激酶抑制劑治療患有分化型甲狀腺癌的患者：M。D。安德森經(jīng)驗。
The results support the hypothesis that activated protein tyrosine kinase receptors are involved in the proliferation of glioma cells.
研究結(jié)果支持了有活性的蛋白酪氨酸激酶受體在腦膠質(zhì)瘤細(xì)胞增殖有關(guān)的假設(shè)。
Objective To evaluate the relationship between glomerular protein kinase C (PKC) and renal alterations under diabetic state.
目的探討糖尿病狀態(tài)下腎小球蛋白激酶C（PKC）與腎臟改變的關(guān)系。
The inactivation and unfolding of arginine kinase by aspartic acid was studied by enzyme activity and fluorescence emission spectra.
應(yīng)用酶活測定、熒光發(fā)射光譜等方法分析了精氨酸激酶在不同濃度天門冬氨酸中活性變化和去折疊動力學(xué)。
The experimental result shows: the soybean protein kinase have fight salt in plant adversity resistance, survival plays an important role.
實驗結(jié)果顯示：此大豆蛋白激酶具有抗鹽抗旱性，在植物的逆境生存中發(fā)揮著重要的作用。
AIM: To explore the relationship of methylation status and expression of spleen tyrosine kinase (Syk) gene in colorectal cancer cell lines.
目的：探討結(jié)直腸癌細(xì)胞中脾酪氨酸激酶基因甲基化和表達的關(guān)系。
The potency ratio to inhibit keratinocyte proliferation follows their potency to inhibit EGF receptor kinase activity in vitro.
藥效比抑制角質(zhì)形成細(xì)胞增殖如下其效力，抑制表皮生長因子受體激酶活性的影響。
Objective To diagnose and treat leukemia, protein tyrosine kinase (PTK) activities were studied in human blood and myelogenic cell.
目的研究人外周血與骨髓細(xì)胞蛋白酪氨酸激酶（PTK）活性，為臨床診斷、治療白血病提供基礎(chǔ)數(shù)據(jù)。
Anti-cancer drugs that jam the enzyme, preventing its docking with the kinase, could halt cell over proliferation to treat such cancers.
干擾此酶的抗癌藥物防止它與激酶對接，可以阻止細(xì)胞過度增殖，從而治療這種癌癥。
In sporophytic SI, two linked loci produce glycoprotein and a kinase that disable each other.
在孢子體自交不親和系統(tǒng)中，兩個連鎖的基因座可以合成糖蛋白和一種讓彼此失活的激酶。
Positive and negative regulation of plant pathogen defense responses has been attributed to mitogen-activated protein kinase cascades.
積極和消極的調(diào)節(jié)植物病原體防御反應(yīng)是由于有絲分裂原活化蛋白激酶級聯(lián)。
