microrna
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例句
Although microRNAs do not code for proteins, they prevent specific genes from giving rise to the proteins they encode.
盡管MicroRNA并不是指導蛋白質合成的密碼,但是他們會阻止一些特定基因的表達(合成相應蛋白質)。
A number of miRNA genes were shown to be located in fragile regions of the human genome that are associated with cancer 8.
研究結果證實,許多microRNA基因存在于那些與癌癥有關的人類基因組脆弱區域。
The microRNA, miR164, has been implicated in aging in Arabidopsis and was part of a complex genetic chain that changed as leaves aged.
其中MIR164這個微RNA,在Arabidopsis的衰老進程中被確認是一個復雜遺傳鏈條的部分,那鏈條隨著樹葉的衰老而變化。
The next step is to find ways to modify this microRNA in the setting of disease and test its ability to alter the disease process.
接下來要做的是怎樣在疾病環境中調控干擾RNA并檢測它改變疾病過程的能力。
However, if a miRNA biomarker fingerprint can be established, a more accurate assessment would be more likely.
然而,如果一個microRNA指紋庫得以建立,更準確的評估將變得可能。
The mature miRNA is incorporated into an RNA-induced silencing complex that binds to a target messenger RNA (mRNA).
成熟microRNA與目標mRNA結合,形成了RNA誘導的基因沉默復合體。
A sera-miRNA fingerprint was determined for colorectal cancer as well.
血清microRNA指紋同樣能很好地診斷結腸癌。
brains of Parkinson's patients to determine which type of microRNA was noticeably deficient in the midbrain regions.
下一步,這些研究人員檢測了帕金森病人死后的腦部以確定哪種信使RNA在中腦區域是明顯缺乏的。
Besides human leukemias and lymphomas, microRNA genes also have been found in human lung, breast and colon cancers .
除了人類的白血病和淋巴癌,人類肺癌,乳腺癌和結腸癌中也發現了微RNA基因。
No study has evaluated the association between microRNA expression patterns and colon cancer prognosis or therapeutic outcomes.
但是現在尚無有關研究來評估microRNA的表達形式與結腸癌預后或治療結果的相關性。
A potential site of action for the microRNAs aligns to an area in a human gene, NR4A3, that encodes a transcription factor protein.
在人類的基因組中有一個部位用于解碼蛋白質轉錄因子,我們稱之NR4A3,是microRNA的潛在作用部分。
Through various techniques, numerous groups have gone on to show that different cancer types have distinct miRNA profiles.
應用各種不同的技術,許多研究小組一直在試圖尋找不同癌癥的特異性microRNA表達譜。
Meanwhile, these studies show that analyzing miRNA levels in serum is a promising area for identifying biomarkers of cancer.
同時,這些研究也證實,血清microRNA的測定是一個檢測癌癥生物學標志物很有前途的領域。
The study examined human pancreatic tumor tissue and compared it to nearby normal tissue and control tissue for levels of microRNA (miRNA).
該研究檢測比較了人類胰腺癌組織與周圍的正常組織和對照組織中小分子RNA(miRNA)水平。
Although first discovered in C. elegans, miRNAs have since been shown to be involved in human cancers 5.
雖然最早在線蟲體內發現,但已經證明,microRNA能參與人類癌癥的發生。
Therefore, it remains elusive if and when there will be room for new, microRNA-based biomarkers.
因此,是否以及何時將有空間給予新的、基于微RNA的生物標記物仍然是難以捉摸的。
The good news is Croce says the technology to manipulate the activity of microRNA already exists.
好消息是,c說抑制微RNA活動性的技術已經存在了。
A more recent paper has also emphasized the role of micro-RNA in hepato-carcinogenesis.
最近有一篇文章則強調了microRNA在肝癌形成中的作用。
This microRNA cluster could represent a new therapeutic target for treating tumors caused by Rb deficiency.
這種miRNA簇可以為治療Rb缺失引致的腫瘤提供新的靶點。
The group also found that in young leaves ORE1 was held in check by microRNA, a kind of small molecule that controls gene expression.
該團隊還發現在年輕樹葉里Ore1含量由微RNA(一種控制基因表達的小分子)控制。
Small pieces of RNA called microRNAs help control gene activity and orchestrate development in plants and animals (ScienceNOW, 8 July 2002).
一種稱為“microRNA”的小片段RNA有助于控制動植物體內的基因活性及其發育。
Furthermore, miRNAs are continuously being shown to act as both oncogenes and tumor suppressors 5.
此外,microRNA基因還不斷被證實扮演著原癌基因和抑癌基因的角色。
Blood samples from 21 volunteers were tested for the presence of microRNAs from crop plants, such as rice, wheat, potatoes and cabbage.
21位志愿者的血液樣本被用來檢測來自各種農作物(比如大米,土豆,和卷心菜)的MicroRNA的存在。
The first serum-miRNA biomarker discovered was miR-21. Lawrie et al.
第一個被發現的血清microRNA標志物是miR-21。
So Crochi's team purposely altered a single type of microRNA gene in lab mice.
所以克里奇的小組在實驗室小鼠身上有目的地改變一個小RNA基因。
Many miRNAs are well conserved across species, suggesting an important role for them.
許多microRNA在不同物種間非常保守,暗示了它們的重要地位。
In the sera of lung cancer patients, there were 63 miRNAs that were not found in normal sera.
在肺癌患者的血清中有63種microRNA是健康人血清中所不存在的。
miRBase (Release 12. 0), the central database for miRNAs, lists over 8 000 miRNAs from plants, animals and viruses.
microRNA的中心文庫——miRBase(Release12.0)包含了超過8000種植物、動物和病毒的microRNA。
A streamlined representation of the interplay between transcriptionfactors in the roundworm. Image: Science
蛔蟲轉錄因子和microRNA之間相互作用的精簡表示。
Effects of MicroRNA 122 on Gene Expression Profiles of Hepatocellular Carcinoma Cells
122對肝癌細胞基因表達譜的影響